Gautam Sethi Selected Research

Stomach Neoplasms (Stomach Cancer)

9/2023	A new triazolyl-indolo-quinoxaline induces apoptosis in gastric cancer cells by abrogating the STAT3/5 pathway through upregulation of PTPεC.
6/2019	Cycloastragenol can negate constitutive STAT3 activation and promote paclitaxel-induced apoptosis in human gastric cancer cells.
1/2018	Corrigendum on "Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer" [Cancer Lett. 363 (1) (2015) 28-36].
11/2015	Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?
10/2015	Isorhamnetin augments the anti-tumor effect of capecitabine through the negative regulation of NF-κB signaling cascade in gastric cancer.
3/2014	Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products.
11/2012	Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer.
4/2012	First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway.
10/2011	Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways.
9/2011	Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4.

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Gautam Sethi Research Topics

Disease

321	Neoplasms (Cancer) 05/2024 - 11/2005
80	Neoplasm Metastasis (Metastasis) 02/2024 - 07/2006
48	Carcinogenesis 01/2023 - 06/2006
40	Breast Neoplasms (Breast Cancer) 12/2023 - 04/2007
39	Inflammation (Inflammations) 05/2024 - 02/2006
35	Hepatocellular Carcinoma (Hepatoma) 12/2023 - 06/2010
27	Multiple Myeloma 01/2022 - 03/2007
16	Prostatic Neoplasms (Prostate Cancer) 02/2024 - 04/2007
13	Lung Neoplasms (Lung Cancer) 09/2023 - 04/2007
12	Chronic Disease (Chronic Diseases) 01/2022 - 06/2007
10	Stomach Neoplasms (Stomach Cancer) 09/2023 - 09/2011
10	Carcinoma (Carcinomatosis) 04/2019 - 04/2007
8	Squamous Cell Carcinoma of Head and Neck 10/2023 - 08/2013
8	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023 - 02/2007
7	Alzheimer Disease (Alzheimer's Disease) 02/2023 - 11/2005
7	Pancreatic Neoplasms (Pancreatic Cancer) 11/2022 - 09/2006
6	Colorectal Neoplasms (Colorectal Cancer) 02/2024 - 01/2016
6	Hematologic Neoplasms (Hematological Malignancy) 02/2024 - 05/2015
6	Mouth Neoplasms (Oral Cancer) 10/2023 - 06/2007
6	Hypoxia (Hypoxemia) 01/2023 - 02/2012
6	Body Weight (Weight, Body) 01/2022 - 01/2012
6	Colonic Neoplasms (Colon Cancer) 01/2022 - 01/2016
6	Leukemia 01/2021 - 03/2006
5	Triple Negative Breast Neoplasms 04/2024 - 03/2016
5	Adenocarcinoma 02/2024 - 10/2011
5	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 06/2023 - 02/2015
5	Arthritis (Polyarthritis) 08/2019 - 11/2005
5	Asthma (Bronchial Asthma) 08/2019 - 04/2011
4	Liver Neoplasms (Liver Cancer) 02/2023 - 11/2010
4	Melanoma (Melanoma, Malignant) 02/2022 - 06/2007
4	Type 2 Diabetes Mellitus (MODY) 01/2022 - 11/2014
4	Necrosis 01/2021 - 06/2007

Drug/Important Bio-Agent (IBA)

54	Proteins (Proteins, Gene)FDA Link 04/2024 - 06/2007
49	Transcription Factors (Transcription Factor)IBA 02/2024 - 03/2006
43	NF-kappa B (NF-kB)IBA 12/2023 - 02/2006
36	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 12/2023 - 05/2007
20	CytokinesIBA 05/2024 - 02/2006
20	Biomarkers (Surrogate Marker)IBA 11/2023 - 04/2014
17	Phosphotransferases (Kinase)IBA 01/2023 - 09/2006
17	MicroRNAs (MicroRNA)IBA 01/2023 - 01/2014
16	PhytochemicalsIBA 04/2024 - 11/2012
14	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2024 - 03/2006
14	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 02/2006
13	EnzymesIBA 01/2024 - 06/2007
13	Matrix Metalloproteinases (MMPs)IBA 01/2023 - 02/2006
12	CateninsIBA 02/2024 - 01/2017
12	AntioxidantsIBA 01/2023 - 01/2011
11	CurcuminIBA 05/2024 - 11/2005
11	LigandsIBA 01/2024 - 11/2010
11	Antineoplastic Agents (Antineoplastics)IBA 01/2023 - 01/2012
11	TriterpenesIBA 06/2019 - 03/2006
10	Therapeutic UsesIBA 01/2024 - 11/2012
10	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2023 - 02/2012
10	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 09/2011
10	Cyclin D1IBA 03/2015 - 02/2006
9	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2023 - 02/2006
9	Bortezomib (Velcade)FDA Link 12/2019 - 05/2007
9	SurvivinIBA 10/2015 - 02/2006
8	Cisplatin (Platino)FDA LinkGeneric 02/2024 - 10/2012
8	ResveratrolIBA 01/2024 - 03/2007
8	celastrolIBA 09/2021 - 04/2007
8	thymoquinoneIBA 01/2018 - 07/2008
7	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 02/2024 - 01/2022
7	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2024 - 06/2007
7	TocotrienolsIBA 02/2024 - 05/2011
7	LipidsIBA 01/2024 - 12/2017
7	AlkaloidsIBA 12/2023 - 07/2008
7	CarcinogensIBA 01/2023 - 11/2006
7	Mitogen-Activated Protein KinasesIBA 01/2021 - 02/2007
7	Ursolic AcidIBA 10/2016 - 09/2007
6	Paclitaxel (Taxol)FDA LinkGeneric 02/2024 - 02/2007
6	Circular RNAIBA 01/2023 - 01/2020
6	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 08/2019 - 02/2012
5	Estrogen ReceptorsIBA 09/2023 - 04/2015
5	QuercetinIBA 02/2023 - 01/2012
5	Ligases (Synthetase)IBA 10/2022 - 01/2018
5	Insulin (Novolin)FDA Link 07/2022 - 11/2014
5	Neuroprotective AgentsIBA 01/2022 - 02/2017
5	TOR Serine-Threonine KinasesIBA 01/2022 - 05/2014
5	Interleukin-6 (Interleukin 6)IBA 01/2021 - 01/2012
5	Cadherins (E-Cadherin)IBA 11/2020 - 12/2016
5	Protein Kinases (Protein Kinase)IBA 11/2019 - 05/2007
5	buteinIBA 02/2017 - 06/2007
5	Emodin (Archin)IBA 01/2017 - 01/2013
4	Peptides (Polypeptides)IBA 04/2024 - 04/2015
4	ChromatinIBA 11/2023 - 09/2011
4	FlavonoidsIBA 04/2023 - 12/2017
4	Long Noncoding RNAIBA 01/2023 - 12/2017
4	PolyphenolsIBA 01/2023 - 06/2007
4	InterleukinsIBA 01/2023 - 03/2006
4	ChemokinesIBA 08/2022 - 02/2006
4	Oncogene Proteins (Oncogene Protein)IBA 08/2022 - 01/2018
4	Histone Deacetylase InhibitorsIBA 09/2021 - 10/2016
4	DiosgeninIBA 09/2021 - 06/2010
4	bergamottinIBA 03/2021 - 11/2014

Therapy/Procedure

134	Therapeutics 04/2024 - 09/2006
33	Drug Therapy (Chemotherapy) 04/2024 - 03/2007
12	Immunotherapy 05/2024 - 10/2019
11	Radiotherapy 01/2024 - 11/2007
5	Precision Medicine 04/2024 - 11/2015